Diffuse nonepidermolytic palmoplantar keratoderma | |
---|---|
Classification and external resources | |
ICD-10 | Q82.8 (ILDS Q82.836) |
OMIM | 600962 |
Diffuse nonepidermolytic palmoplantar keratoderma (also known as "Diffuse orthohyperkeratotic keratoderma," "Hereditary palmoplantar keratoderma," "Keratosis extremitatum progrediens," "Keratosis palmoplantaris diffusa circumscripta," "Tylosis," "Unna–Thost disease", and "Unna–Thost keratoderma"[1]) is inherited as an autosomal dominant condition and is present from infancy, characterized by a well-demarcated, symmetric, often "waxy" keratoderma involving the whole of the palms and soles.[2]:506-8[3]:213